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Kidneys and bladder

Fanconi syndrome

Fanconi syndrome is a disorder of the kidney tubules in which the kidneys can no longer return to the blood substances the body should keep, such as glucose, salts and amino acids. These substances are lost in the urine, so the body starts to run short of them. Over time the condition can damage the kidneys.

Updated

3 breeds

What it is

The kidneys filter the blood through a vast number of tiny filtering units called nephrons. Each one first filters out water and small substances, then its tubules take back what the body needs. In Fanconi syndrome the tubules stop doing this job, so glucose, salts, amino acids and bicarbonate leak away in the urine. Fluid is lost with them, which is why the dog drinks so much, and the blood can gradually become too acidic.

The syndrome can be inherited, in which case the signs appear in young adult or middle-aged dogs, or it can be acquired, for example after exposure to certain toxic substances.

A dog with this syndrome needs fresh water within reach at all times and plenty of chances to go outside to pee. It also needs regular check-ups with a vet, so between visits keep a note of how much your dog drinks and how its weight changes.

Signs you may notice

You may notice a dog that drinks and urinates much more, loses weight, becomes listless and has a dull coat. If a dog starts drinking unusually large amounts, it is worth having it seen by a vet.

When to see a vet

Book a visit if your dog starts drinking or peeing noticeably more, or loses weight for no clear reason. If it stops eating, vomits repeatedly or becomes very weak, it should be seen by a vet the same day.

This is general information, not veterinary advice. For your own dog's health, tests and treatment, see a vet.

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