Skip to content
Kidneys and bladder

Cystinuria

Cystinuria is an inherited metabolic disorder in which the kidneys fail to reclaim an amino acid called cystine, so it passes into the urine. Cystine dissolves poorly in urine, so it can form crystals and stones in the kidneys or bladder. A stone can get stuck and block the urinary tract, and a dog that cannot pass urine needs a vet immediately.

Updated

1 breed

What it is

Cystine is one of the building blocks of protein. Healthy kidneys filter it out of the blood and then draw it back in before the urine leaves the body. In cystinuria an inherited fault breaks that reclaiming step, so cystine stays in the urine, where it dissolves poorly. In acidic, concentrated urine it settles out as flat, six-sided crystals that can clump together into stones.

The fault is there from birth, but stones take time to build up, so trouble may only appear once the dog is grown. Males face a greater risk of a blockage, because their urethra is longer and narrower.

Living with a dog that has cystinuria means keeping an eye on its toilet habits. On each walk, take a moment to see how your dog urinates and what the urine looks like: noticing a change early matters far more than any single day's worry.

Signs you may notice

You may notice the dog asking to go out more, straining for a long time but passing only a few drops, or blood in the urine. If the dog tries to urinate but nothing comes out, don't wait: take it to a vet right away.

When to see a vet

A dog that strains but cannot pass any urine needs a vet immediately. Book a visit for blood in the urine or straining that comes and goes.

This is general information, not veterinary advice. For your own dog's health, tests and treatment, see a vet.

More conditions: Kidneys and bladder

Also worth knowing for the same breeds

Conditions the same breed guides mention.