What it is
Cells constantly break down and recycle material, and much of this work happens in small compartments called lysosomes, which act like recycling centres. In a storage disease the cell lacks an enzyme it needs to break down a particular substance, so that substance piles up. The cells swell and stop working properly, and nerve cells, which have to last a lifetime and cannot be replaced, suffer in particular.
These diseases are inherited, and parents that carry the faulty gene can look perfectly healthy. The signs appear in puppies or young dogs and become more marked over time.
A dog with a storage disease needs a calm, safe home: soft bedding, gates at stairs and drops, and, if its sight is failing, furniture kept in the same places. Note down new signs, such as trembling, stumbling or changes in behaviour, so you can tell your vet.
Signs you may notice
- Grows slower than littermates
- Clumsy or wobbly movement
- Trembling, especially of the head
- Changes in behaviour
- Poorer eyesight
- Seizures
You may notice a young dog growing poorly, moving clumsily or unsteadily, trembling, behaving differently or seeing less well. The signs become more marked over time, and some dogs develop seizures.
When to see a vet
Book a visit if a puppy or young dog grows poorly, becomes clumsy, trembles or starts behaving differently. If your dog has a seizure, a vet is needed immediately.
This is general information, not veterinary advice. For your own dog's health, tests and treatment, see a vet.